Evaluation of the Rewarding Effects of Mitragynine vs the Benefits of Highly Potent 7-Hydroxymitragynine Kratom

7-hydroxymitragynine, a potent alkaloid found in the kratom plant, is increasingly gaining attention for its unique properties and benefits. Compared to its more commonly known counterpart, mitragynine, 7-hydroxymitragynine offers significantly higher potency and distinct effects for the user.

In this comprehensive guide, Real Botanicals explores:

• The unique history of 7-hydroxymitragynine alkaloids

• Benefit of ChromaPure™ extraction over other methods

• 7-Hydroxy's uses and benefits (and how it compares to mitragynine & other kratom alkaloids)

• Best 7-hydroxymitragynine products—Real Botanicals' 7-Hydro! 

 

What Is 7-Hydroxymitragynine?

Kratom has traditionally been used in Southeast Asia for centuries, where tropical trees (Mitragyna speciosa korth) grow in their native soils. Traditionally, leaves of the kratom tree were chewed or brewed into tea, but now there are a vast number of kratom products, 7-OH products, and the like, available for purchase online or in specialty stores across the US.

In the late 20th century, Western scientists discovered the primary alkaloid, mitragynine, and subsequently, 7-hydroxymitragynine, both active components in kratom responsible for its therapeutic effects. While present in small quantities as an alkaloid in kratom leaf, 7-hydroxymitragynine is also an active metabolite of mitragynine, formed in the body when liver enzyme P450 3A4 converts mitragynine into 7-hydroxymitragynine or 7-OH.  

Did you know? Some studies have demonstrated analgesic effects, likely due to the high affinity of 7-OH to receptors in the brain. In fact, many studies have analyzed the potent antinociceptive and weak rewarding effects in mice—in case you want a rabbit hole to throw yourself into today. It's all really quite fascinating!

An Alkaloid by Many Names

In the world of kratom, there are many names and pronunciations for kratom and its components, so it may be hard to determine if your product contains 7-hydroxymitragynine (or extracts of it).

Look on the product labeling for any of these terms: 

• 7-hydroxymitragynine

• 7-hydroxy mitragynine

• Hydroxymitragynine

• 7-Hydroxy

• 7-Hydro

• 7-OH

• 7-OHM

The total alkaloid content of a kratom product may contain a number of kratom alkaloids: 

• Mitragynine (sometimes written as MIT)

• 7-hydroxymitragynine

• Paynantheine

• Speciogynine

• Speciociliatine

• And more

Mitragynine constitutes the majority, with the much more potent 7-hydroxymitragynine occurring in only a tiny percentage. The product you are using may not specify which alkaloids are present, and just say "Mitragyna speciosa leaf" in the ingredients. In this case, contact the company for a more precise ingredient list.

Are you curious about where to buy kratom near you? Right here with any of the Real Botanicals products. We are always transparent with kratom's potential benefits and what is in our products!

 

What Is 7-Hydroxymitragynine Used For?

Most kratom users are familiar with the rewarding effects of mitragynine, but many do not know much about what the minor kratom constituent 7-hydroxymitragynine can do. Since its isolation from other kratom compounds (in the late 20th century), we've learned much more about the power and effects of 7-hydroxymitragynine, most notably that 7-hydroxymitragynine is significantly stronger than mitragynine and the other kratom alkaloids.

• Up to 17X stronger than mitragynine.

• Best alkaloid for mood support & relief from discomfort.

• It may give that notable "feel good" effect.

• Like mitragynine, at lower doses, it induces stimulatory effects. But higher doses are more potentially sedating than that of mitragynine.  

• Economical! Far more potent = less product needed. (A benefit for those who have trouble digesting a lot of plant material.)

Note on 7-Hydroxymitragynine dosage: Start with small doses of 7-OH products due to the high potency and substantial effects. Some may describe 7-OH as having opioid-like effects. Even low doses of 7-hydroxymitragynine can have notable effects! A high dose of 7-hydroxymitragynine may offer high relief but may have sedative effects that are too strong for some users.  

Unique Perspectives on Alkaloid Interactions

The synergistic interaction between these alkaloids is seldom discussed in the industry. While 7-hydroxymitragynine benefits provide potent effects, its interaction with other kratom alkaloids can modulate its overall impact, enhancing benefits while potentially mitigating risks. This interplay suggests that kratom’s effects cannot be attributed to a single alkaloid. Therefore, the combined effects of mitragynine and 7-hydroxymitragynine (plus other minor alkaloids) provide a full spectrum and well-rounded appeal for kratom use. Understandably, this suits most kratom users. 

Even so, some kratom users who want the most relief-oriented kratom experience may turn to kratom products infused with extra 7-hydroxymitragynine, providing a more potent kratom to mitragynine products, or those that contain a full suite of alkaloids.

Let's take a closer look at how 7-hydroxymitragynine alkaloids measure up to the other active components of kratom leaf.

 

Comparing 7-Hydroxymitragynine to Other Kratom Alkaloids

7-Hydroxymitragynine is often compared to other prominent kratom alkaloids, primarily mitragynine, due to its distinct properties and potent effects. While both alkaloids are derived from the kratom plant, they exhibit different characteristics and benefits that make them unique. 

Mitragynine vs. 7-Hydroxymitragynine

The indole alkaloid mitragynine is the most abundant alkaloid in kratom leaves and has been extensively studied for its relaxing and stimulating effects. It is the precursor to 7-Hydroxymitragynine, which is formed through metabolic processes in the liver. These two alkaloids differ in their potency, effects, and potential risks. 

Check out the full article: Difference Between Mitragynine and 7-Hydroxymitragynine: The Real Truth Behind Mitragynine vs 7-Hydroxymitragynine.  

Mitragynine vs 7-Hydroxymitragynine Comparison Chart

Below is a comparison table highlighting the key differences between mitragynine and 7-Hydroxymitragynine:

 

The journey of 7-hydroxymitragynine from a traditional remedy to a subject of modern scientific research highlights its enduring value and evolving understanding. Its discovery and the subsequent insights into its properties have opened new avenues for discomfort management and mood support. 7-hydroxymitragynine's diverse applications, from mood enhancement to cognitive function, underscore its versatility. Additionally, unique benefits such as improved sleep and enhanced social interaction make it a compelling choice for those seeking holistic wellness.

Other Alkaloids in Kratom

While mitragynine and 7-hydroxymitragynine are the most well-known, kratom contains several other alkaloids that contribute to its overall effects. These include:

• Paynantheine: Acts as a relaxant and contributes to the overall calming effects of kratom.

• Speciogynine: Another relaxant that aids in relieving tension and promoting relaxation.

• Speciociliatine: Has mild effects and contributes to the calming properties of kratom.

A Word on Avoiding Drug and Alcohol Dependence Complications

While the therapeutic potential is higher with 7-OH, its use isn't without caution. Due to its potency, it may appeal to those seeking discomfort relief, but be aware that its potency can present a higher potential for abuse if not used properly. Chronic use or use in high quantities may lead to dependence or withdrawal symptoms. Knowing about this abuse potential helps you to make informed decisions about how you use kratom for the best results.

Never combine the use of kratom extracts, mitragynine (MIT), or 7-hydroxymitragynine (7-OH) with alcohol or recreational drugs, especially any that interact with opioid receptors. Discuss any other substances you use with your doctor and follow their guidance.

 

The Best 7-Hydroxymitragynine Kratom: Real Botanicals' 7-Hydro

For purity, potency, and reliability, Real Botanicals' 7-Hydro maximizes the power of 7-hydroxymitragynine, producing a significantly more impactful kratom than the combined effects of mitragynine and other alkaloids found in regular kratom.

Shop 7-OH Products Here: 

7-Hydro Tablets

7-Hydro Shots

The refinement and extraction process of 7-hydroxymitragynine from kratom leaves is a sophisticated procedure that ensures the highest quality and potency of the final product. Many companies outsource extraction and purification, but here at Real Botanicals, we use a hands-on approach to ensure that excellence is maintained at every level. This is how we make 7-Hydro products that consumers love using and feel safe enjoying!

Real Botanicals' Top-of-the-Industry Extraction & Production

The process of extracting 7-Hydroxymitragynine from kratom leaves involves several critical steps that require precision and expertise. Here is an overview of the modern extraction techniques used to isolate this potent alkaloid:

• Harvesting: The process begins with the careful selection and harvesting of mature kratom leaves. The harvest timing is crucial, as the alkaloid content varies depending on the leaf’s maturity and the time of year.

• Drying: Once harvested, the leaves are thoroughly dried in controlled conditions to preserve their alkaloid content. Proper drying methods prevent the degradation of sensitive compounds.

• Powdering: The dried leaves are then finely powdered to increase the surface area for extraction, ensuring maximum efficiency in the subsequent steps.

• Solvent Extraction: The powdered leaves undergo solvent extraction, where a suitable solvent (such as ethanol or water) dissolves the alkaloids. This mixture is then filtered to remove plant material, leaving behind a concentrated alkaloid solution.

• Purification: The concentrated solution is subjected to further purification processes, such as chromatography, to isolate 7-hydroxymitragynine. Chromatography techniques, including high-performance liquid chromatography (HPLC), separate and purify the alkaloid with high precision.

• Crystallization: The final step involves crystallizing the purified 7-hydroxymitragynine, producing a highly concentrated and potent product.

7-Hydroxymitragynine Extraction: ChromaPure™ Does it Best

One of the key differentiators for Real Botanicals 7-Hydro is using the ChromaPure™ extraction process. This advanced chromatography technique meticulously isolates 7-hydroxymitragynine, eliminating contaminants and ensuring maximum purity. The result is a product with unparalleled potency, providing users with the full benefits of this potent alkaloid without any unwanted impurities.

High-quality extraction techniques are vital for several reasons:

• Safety: Ensuring the purity of 7-hydroxymitragynine minimizes the risk of contamination, which can lead to adverse effects. High-quality extraction processes remove harmful substances, making the product safer for consumption.

• Efficacy: The potency of 7-hydroxymitragynine is directly linked to the extraction process. Proper extraction ensures concentrations, efficacy, and benefit to the user.
  
  

• Consistency: This ensures each batch of 7-hydroxymitragynine has the same composition and potency.

The Real Botanicals Guarantee

One of the key challenges in the extraction process is ensuring the purity and potency of 7-hydroxymitragynine without losing alkaloid integrity or concentration. Further, Real Botanicals prioritizes customer safety and satisfaction. To make these promises to you, we use advanced techniques and stringent quality control measures: 

• Ethical Sourcing and Sustainability: Real Botanicals is dedicated to ethical sourcing and sustainability, practices often overlooked in the kratom industry. We source our kratom leaves from sustainable farms that prioritize environmental responsibility and fair labor practices. This ethical approach supports the well-being of local communities and ensures our kratom is grown in optimal conditions, enhancing its quality.

• ChromaPure™ Process: The refinement and extraction process of 7-hydroxymitragynine is a complex and meticulous procedure that demands expertise and precision. Our ChromaPure™ process is a cutting-edge chromatography technique that achieves the highest levels of purity and potency and ensures the perfection of the final product. 

• Laboratory Testing: Each batch of 7-hydroxymitragynine undergoes rigorous testing in third-party laboratories to verify its cleanliness and ensure its potency.

• Standardized Procedures: The extraction and refinement processes are standardized to maintain consistency across all batches, guaranteeing the highest quality standards are met for every product you buy from us.

This dedication to excellence is what makes Real Botanicals a trusted choice for anyone who is looking for high-quality kratom products. With us, you never have to worry about what's in your kratom products! 

Flying with kratom? Our 7-Hydro Travel Tube simplifies travel or flying with kratom!

Choose Real Botanicals' 7-Hydro for High-Powered Wellness Support

From its historical roots in Southeast Asia to its modern-day refinement and application, 7-hydroxymitragynine stands out as a potent and versatile compound, thanks, in part, to our ChromaPure™ process. When compared to other kratom alkaloids, Real Botanicals 7-hydroxymitragynine's superior potency and efficacy are evident. Its distinct properties offer advantages that are not only powerful but also nuanced, providing a more comprehensive approach to natural health management. 

Hydroxymitragynine alkaloids are starting to make big waves in the kratom industry, and we're happy to be ahead of the game (for you!). Our 7-Hydro products are poised at the forefront of this exciting field, providing reliable and effective health and wellness aids so you can live your life more comfortably. Welcome to the family here at Real Botanicals, where we get REAL about kratom!